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Acute Respiratory Distress Syndrome (ARDS) Advanced - Diagnosis | Clinical Medicine

Acute Respiratory Distress Syndrome (ARDS) diagnosis can be complex, but is critically important. In this video, we dive into the complexities of diagnosing ARDS. We discuss the Berlin Criteria as a diagnostic approach before transitioning into the newer Global Definition of ARDS published in 2024. We compare and contrast these two diagnostic frameworks, review real-world examples, and discuss how to apply this clinically.
Introduction, Previous ARDS Videos, Patreon Community
Berlin Criteria for Diagnosing
Introducing the New Global ARDS Diagnostic Criteria, ARDS Pathophysiology
First Three Diagnostic Criteria, Timing, Chest Infiltrates, Acute Event, Origin of Infiltrates
Non-intubated vs Intubated, SpO2 to FiO2 ratio compared to PaO2 to FiO2 ratio
New Global Diagnostic Criteria compared to Berlin Criteria
Real World Examples, Practice Questions
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YouTube Video:
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Acute Respiratory Distress Syndrome (ARDS) Advanced - Phenotypes | Clinical Medicine

In this podcast, we explore the different phenotypes of Acute Respiratory Distress Syndrome (ARDS), with a focus on severity, clinical, biomarker, and physiologically derived phenotypes. We dive into hyper inflammatory and hypo inflammatory phenotypes including their morbidity, mortality, and management differences. ARDS is a critical condition that requires timely and precise intervention to improve patient outcomes. Whether you're a healthcare professional, a medical student, or someone interested in respiratory care, this video provides an in-depth analysis of the best practices and latest research in ARDS phenotypes.
Introduction, Previous ARDS videos (linked below)
Background, Phenotyping in medicine, Berlin diagnostic criteria, Why this matters
ARDS phenotyping, severity phenotypes with P/F ratios, clinical and radiographic phenotypes, biologic phenotypes (hyperinflammatory and hypoinflammatory phenotypes)
Hypoinflammatory versus hyperinflammatory ARDS phenotypes, morbidity, mortality, PEEP approaches, fluid approaches, and how to diagnose each of these
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YouTube Video:
https://www.youtube.com/watch?v=qjiJjViT8Q4 
 

Acute Respiratory Distress Syndrome (ARDS) Advanced - Management | Clinical Medicine

In this podcast, we explore the management of Acute Respiratory Distress Syndrome (ARDS), with a focus on evidence-based strategies and insights from the respective medical studies. ARDS is a critical condition that requires timely and precise intervention to improve patient outcomes. Whether you're a healthcare professional, a medical student, or someone interested in respiratory care, this video provides an in-depth analysis of the best practices and latest research in ARDS management.
Overview of management strategies
General management approach, lung protective ventilation, permissive hypercapnia, barotrauma, atelectotrauma
6cc/kg IBW, plateau pressure 30, ARDS Network Trial
Low PEEP/High FiO2 vs High PEEP/Low FiO2, ALVEOLI Trial, PEEP Tables
Proning, P:F ratios, PROSEVA Trial
Paralysis/Neuromuscular blockade, ROSE Trial, ACURASYS Trial
Conservative fluid strategies, ARDS Clinical Network Trial
Steroids, DEXA-ARDS Trial
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YouTube Video:
https://www.youtube.com/watch?v=6YC0qrpQ8j8 
 

Acute Respiratory Distress Syndrome (ARDS) Advanced - Pathophysiology | Clinical Medicine

In this podcast, we explore the advanced pathophysiology of Acute Respiratory Distress Syndrome (ARDS), diving deep into the molecular mechanisms and cellular processes that drive the progression of this life-threatening condition. Understanding ARDS at the pathophysiological level is critical for effective management and treatment in clinical settings.
Introduction to inflammatory response, diffuse alveolar damage, capillary alveolar barrier, matrix repair, profibrotic response
Exudative phase including endothelial and epithelial damage, inflammatory response, proteinaceous leak, loss of surfactant, micro thrombi
Proliferative phase including neutrophil clearance, matrix repair, alveolar repair, type 1 and 2 pneumocytes, removal proteinaceous fluid
Fibrosing phase including fibroblast proliferation, hyaline membranes, profibrotic pathway
Heterogeneity of ARDS, CT findings, VQ mismatch, shunting, diffusion coefficients, and dead space
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YouTube Video:
https://www.youtube.com/watch?v=-gNGMTCPEuc 
 

Acute Respiratory Distress Syndrome (ARDS) - Basics | Clinical Medicine

In this video, we break down the basics of Acute Respiratory Distress Syndrome (ARDS)—a life-threatening condition that causes severe difficulty breathing. Whether you’re a healthcare professional, a student, or just looking to understand more about this condition, this podcast covers everything you need to know about ARDS.
What is ARDS and who does it affect?
Causes of ARDS including pulmonary and non-pulmonary
Pathophysiology of ARDS including the three stages (exudative, proliferative, and fibrotic)
Diagnosing ARDS including Berlin Criteria, PF ratios, and imaging findings
Management of ARDS including cardiac support, multi organ injury, severity by PF ratio, lung protective ventilation, proning, fluids
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YouTube Video:
https://www.youtube.com/watch?v=Fj_wXSJsCag  
 

Left Ventricular Assist Device Advanced - Evaluating and Managing Suction Events | Clinical Medicine

LVADs are amazing devices that can increase blood flow around the body for those with end stage heart failure. They are very complex though. Suction events are when the cannula sucking blood out of the left ventricular has trouble suctioning that blood. In this video we dive into how to evaluate and manage LVAD suction events.
Introduction, Basics, Overview
What Is A Suction Event, Anatomy, LVAD Mechanics
Causes Of Suction Events, Evaluating And Managing Them - Inflow Cannula Position, Speed Changes, Hypovolemia, Arrhythmia, GI Bleed, Right Ventricular Failure, and More!
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YouTube Video:
https://www.youtube.com/watch?v=QFZNrOP6nZY 
 

LVAD Basics - Anatomy/Physiology, Indications, Contraindications, Evaluation | Clinical Medicine

Left Ventricular Assist Devices (LVADs) are surgically implanted devices that pull blood from the left ventricular and push it into the aorta to support patient's with end stage heart failure. Its role is expanding as it has demonstrated improved mortality and symptoms for those with end stage heart disease. In this video we dive into the basics of LVADs including the anatomy, physiology, indications, contraindications, and evaluation.
Introduction, Heart Failure, Who Benefits Most
Anatomy, Physiology, Inflow/Outflow, Motor, Components
Indications, Bridge to Transplant, Decision, Recovery, or Destination Therapy
Contraindications - Right Heart Failure, Bleeding, Coexisting Terminal Illness, Neurologic Compromise, Anatomic and Technical Limitations, and More
Pump Parameters - Speed, Flow, Power, Pulsatility Index
Evaluation, Bedside Parameters, Blood Pressure, Labs, Work Up
Complications - Bleeding, Gastrointestinal Bleeding, Sepsis, Infection, RV Failure, Aortic Regurgitation, Stroke
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YouTube Video:
https://www.youtube.com/watch?v=L1Vm72M4Dzw
 

Hantavirus Basics - Cases, Reservoir, Transmission, Incubation, Symptoms, Prevent | Public Health

We delve deep into Hantavirus, a deadly virus that can cause serious diseases like Hantavirus Pulmonary Syndrome (HPS) and Hemorrhagic Fever Renal Syndrome (HFRS). Learn about the Hantavirus cases reported in USA and Europe, its natural reservoirs, and how the virus is transmitted through rodent urine, droppings, and saliva. We also discuss the incubation period, the common symptoms of Hantavirus infection, and the importance of early diagnosis and treatment. Preventive measures are essential to avoid infection.
Discover key tips on how to protect yourself and your family from Hantavirus exposure, especially in areas with high rodent populations.
Key Topics Covered:
- What is Hantavirus and its significance in public health.
- Transmission routes and how it spreads through the environment.
- The incubation period and early warning signs of infection.
- Symptoms of Hantavirus Pulmonary Syndrome (HPS) and related conditions
- How to diagnose and treat Hantavirus infections.
- Essential prevention tips to minimize the risk of exposure.
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YouTube Video:
https://www.youtube.com/watch?v=94I52t-MMK8 
 

Measles Basics - Symptoms, Transmission, Incubation, Diagnosis, Treat, Prevent | Public Health

Measles is one of THE MOST contagious viruses on the planet. Learn about all things Measles Virus in this high yield podcast!
Outbreaks, Yearly Cases, Global Cases
Virology, Fusion Protein, Viral Family
Symptoms, Rashes, Koplik Spots With Pictures
Incubation Period, When Most Contagious, Transmission
Diagnosis, Serology, PCR Swabbing, Treatment, Vitamin A, Supportive Care
Complications, Pneumonia, Encephalitis, Subacute Sclerosing Panencephalitis
Prevention, Vaccination, Efficacy, Post Exposure Prophylaxis
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YouTube Video:
https://www.youtube.com/watch?v=Xe9VKlbbAcM 
 

E. Coli Basics - Outbreaks, Diseases, Symptoms, Transmission, Treat, Prevent | Clinical Medicine

Escherichia coli, more commonly known as E. coli, has been behind numerous outbreaks both currently and in past years. It is a normal bacteria in all of our gastrointestinal tracts, but also can be the cause of numerous different diseases. In this video, we dive into all things E. coli!
Outbreaks, past and present
What is E. coli? Different strains, bacterial structure, explaining O:H schema, ETEC, EPEC, EIEC, EHEC/STEC, and more!
 E. coli caused diseases including UTI, pneumonia, peritonitis, bacteremia, sepsis, diarrheal illnesses, travelers diarrhea, and more.
Hemolytic Uremic Syndrome (HUS) explained
Transmission and at risk groups
Treatments and prevention
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YouTube Video:
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