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New Threat: Bird Flu D1.1 Strain Infects Cows, Spreads to Humans in Nevada | Public Health

A new and potentially concerning development has emerged as the Bird Flu strain D1.1 has jumped from birds to cows and has now infected a human in Nevada. This event raises questions about the potential for additional cross-species transmission. Is there a risk of a larger outbreak? In this video, we explore the details of this case, how the virus is spreading, additional mutation found in this D1.1 variant making it more efficiency for mammalian infection, and what this means for public health.
Key topics covered:
(1) The evolution of Bird Flu H5N1 variant D1.1 and its mutation to go from infecting birds to infecting cows
(2) How the virus moved from birds to cows, and then to humans
(3) What this means for human health and the risk of future infections
(4) The Nevada human infection case: What you need to know Is this the beginning of a new pandemic threat, or a rare, isolated incident? 
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YouTube Video:
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Bird Flu H5N1 Variant Identified Resistant to Oseltamivir (Tamiflu)

In this podcast, we explore the emergence of a Bird Flu variant resistant to the common antiviral oseltamivir (Tamiflu), which is the main treatment for Bird Flu in humans. This variant was identified in several flocks in Canada. It is interestingly not the first time we have identified a variant of Bird Flu resistant to treatment. Check out the podcast for these details and more!
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YouTube Video:
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Marburg Virus - Ebola's Cousin Creates Stir - Disease, Symptoms, Transmission, Outbreaks, Treatment

Marburg Virus is now responsible for two recent outbreaks and the CDC put out a statement warning healthcare providers to be on alert. Here, we do a deep dive on Marburg Virus.
Marburg Virus is from the same viral family as Ebola virus, the Filoviridae. It causes Marburg Virus Disease (MVD), one of the viral hemorrhagic fevers. We discuss the symptoms and incubation period of Marburg Virus. How it is transmitted both between bats and humans, as well as human to human transmission. We touch on prevention strategies and treatment possibilities. And finally we dive into the history of the virus, previous outbreaks, and the current outbreaks. Should we be worried?
New Headlines And Relation To Ebola
Viral Structure And Properties
Marburg Virus Disease, Incubation, Symptoms
Zoonotic Transmission To Humans
Human To Human Transmission And Prevention
Treatment, Vaccines, Previous Outbreaks
Current Outbreaks, Should We Be Worried?
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YouTube Video:
https://www.youtube.com/watch?v=hoKVoJhRWvg 
 

Bird Flu Variant in Cats: PB2 Gene Mutation Raises Concerns - What You Need to Know | Public Health

A new bird flu variant in cats has been discovered, and it carries a concerning mutation in the PB2 gene. This mutation could have significant implications for both animal health and public health, as it may increase the risk of the virus spreading more easily across species, including potential transmission to humans.
In this video, we break down:
- What the PB2 gene mutation is and how it affects the bird flu virus (avian influenza).
- The potential risks of this mutation in cats and its implications for public health.
- How avian influenza is transmitted, and why this new variant is a cause for concern.
- What we know about bird flu outbreaks in animals and the role of zoonotic diseases.
- Transmission potential from cats to humans
- Previous cases of bird flu with the PB2 mutation
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YouTube Video:
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Update On Bird Flu - Overview On All Things Avian Influenza | Public Health

In this comprehensive video, we dive into the latest updates on Avian Influenza (Bird Flu) from a doctor's perspective. From current outbreaks to preventive measures, symptoms, treatment, and public health implications, this video covers everything you need to know about the virus.
Stay informed on:
- What the virus is and how it spreads
- The status of bird flu outbreaks in the USA and globally
- Animals infected and risks for humans
- How Avian Influenza spreads and its impact on poultry and humans
- Symptoms, diagnosis, and treatment options
- The role of public health in controlling the spread of the virus
- What you can do to stay safe
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YouTube Video:
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Pulmonary Embolism Advanced - Management Strategies And Risk Stratification | Clinical Medicine

In this podcast, we dive into advanced management strategies for pulmonary embolism (PE), focusing on the latest techniques and protocols for diagnosis and treatment based on risk stratification. Pulmonary embolism is a life-threatening condition that requires quick and effective management to prevent severe complications. Understanding the various approaches to PE treatment, including pharmacological and non-pharmacological methods, is crucial for healthcare professionals involved in clinical medicine.
Low, Intermediate Low, Intermediate High, High Risk PE
Low Risk PE, Diagnosis, Treatment
Intermediate Low Risk PE, Diagnosis, Treatment
Intermediate High Risk PE, Diagnosis, Treatment
High Risk PE, Diagnosis, Treatment
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YouTube Video:
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Mechanical Ventilation Basics - Ventilator Induced Lung Injury (VILI) | Clinical Medicine

In this video, we dive into Ventilator-Induced Lung Injury (VILI), a serious complication that can arise from mechanical ventilation in critically ill patients. Understanding the causes, mechanisms, and prevention strategies is crucial. We talk about multiple types of VILI including volutrauma, barotrauma, biotrauma, ergotrauma, atelectrauma. Learn all things VILI in this high yield podcast!
Mechanical Ventilation, Lung Injury
Mechanism, Optimal Alveolar Distension, Alveolar and Airway Damage
Types of VILI, Barotrauma, Atelectrauma, Volutrauma, Ergotrauma, Biotrauma and their Treatment
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YouTube Video:
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Cardiac Arrest Basics - Overview | Clinical Medicine

Cardiac arrest affects hundreds of thousands of people in the USA alone, millions worldwide, each year. This is the most deadly of diseases and requires immediate, high quality interventions to have a chance at meaningful survival. Learn the basics of cardiac arrest including incidence, causes, rhythms, survival and emergency management
Incidence, In-Hospital vs Out-Of-Hospital, Bystander CPR, Bystander AED Use, Adults vs Children
In-Hospital Cardiac Arrest (IHCA) vs Out-Of-Hospital Cardiac Arrest (OHCA)
Pathophysiology, Organ Injury and Failure, Tissue Hypoxia
Rhythm Analysis, Shockable vs Non-Shockable, Vfib, Vtach, Asystole, PEA
Causes, H's and T's, Cardiac and Non-Cardiac Causes
Basics of Management, Chest Compressions, Early Defibrillation
Prognosis, IHCA vs OHCA, Neurological Outcomes, ROSC, Survival
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Oxygen Hemoglobin Dissociation Curve - Comprehensive and Clear Explanation!

The Oxygen Hemoglobin Dissociation Curve, also known as the Oxyhemoglobin Dissociation Curve, is a critical concept. Understanding this provides a foundation for a number of pathophysiologic processes key in the understanding of physiology.
In this podcast, we dive into these concepts. We start by discussing what makes up oxygen content in the blood and how that differs between the arterial system and venous system. We discuss gas exchange of oxygen and carbon dioxide at the capillary level. We then define key concepts like oxygen content (with the equation), dissolved oxygen (PaO2), oxygen saturation (SaO2, SpO2). We dive into red blood cells, hemoglobin (subunits), oxygen binding capacity of hemoglobin, tense vs relaxed states, tissue-lung interface, and more. After that, we use all of these concepts to establish what the normal oxyhemoglobin dissociation curve is before discussing abnormal including left shifts, right shifts, Bohr's Law, and more!
Introduction to Capillary Gas Exchange, Arterial vs Venous Systems, Oxygen Content
Defining Oxygen Content, Oxygen Saturation (SaO2, SpO2), Dissolved Oxygen (PaO2)
ed Blood Cells, Hemoglobin Structure (subunits), Oxygen Binding Capacity, Tense vs Relaxed, Lung Tissue Interface
Relationship Between SaO2 (SpO2) and PaO2 or Oxygen Saturation and Dissolved Oxygen
Normal Oxyhemoglobin Dissociation Curve
Right Shift, Left Shift, Bohr's Law, Bringing it all Together
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Mechanical Ventilation Basics - PEEP, FiO2, Respiratory Rate, Tidal Volume | Clinical Medicine

Mechanical ventilation has many different modes and settings. In this podcast we dive into the foundational settings that everyone should know - PEEP, FiO2, Respiratory Rate, Tidal Volume, and Inspiratory Pressure. We touch on how these settings may differ between modes of ventilation, such as volume control and pressure control. We talk about normal values and ranges of values. We also discuss which settings help ventilation versus oxygenation. Start to master these topics in this podcast!
Ventilator Screen Layout
Positive End Expiratory Pressure (PEEP)
Fraction of Inspired Oxygen (FiO2)
Respiratory Rate
Tidal Volume or Inspiratory Pressure above PEEP
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