WhiteBoard Medicine - Emergency And Critical Care

#89 Transfusion Medicine Basics - Fresh Frozen Plasma FFP | Clinical Medicine

In this podcast, we provide an in-depth overview of Fresh Frozen Plasma (FFP), a crucial component in transfusion medicine. FFP is used to treat various clotting disorders, and understanding its indications, preparation, and clinical application is vital for healthcare professionals.
🔬 What is Fresh Frozen Plasma (FFP)?
💉 Indications for FFP transfusion: Coagulation factor deficiencies, liver disease, trauma, and more
⚠️ Clinical considerations: Risks, complications, and transfusion reactions
🩺 FFP administration: Proper use, dosage, and safety protocols
💡 Role of FFP in clinical practice: How it supports hemostasis and improves patient outcomes
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=LWXn_v0KAj8 
 

#88 Transfusion Medicine Basics - Packed Red Blood Cells | Clinical Medicine

In this podcast, we provide a clear and concise overview of packed red blood cells (PRBC), a critical component in transfusion medicine. Understanding when and how to use PRBCs is essential for clinicians, especially in managing anemia, hemorrhagic shock, and other conditions requiring blood transfusion.
🎯 What are Packed Red Blood Cells (PRBCs)?
💉 Indications for PRBC transfusion: Anemia, blood loss, and other clinical scenarios
🔬 How PRBC transfusions work: The physiology behind RBC transfusion and their role in oxygen delivery
⚠️ Risks and complications of blood transfusions: Transfusion reactions, infections, and more
🩺 Clinical considerations: Guidelines for safe and effective blood transfusion practice
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=sX-FfZoOueg 
 

#87 Sepsis Advanced - Sepsis Phenotypes | Clinical Medicine

In this podcast, we explore the concept of sepsis phenotypes, which refer to the distinct biological and clinical presentations of sepsis that can influence treatment decisions, prognosis, and patient outcomes. Understanding these phenotypes is critical for personalized medicine and improving the management of sepsis.
🧬 What are sepsis phenotypes?
🔬 Clinical sepsis phenotypes: alpha, beta, gamma, delta
💡 Clinical manifestations: How sepsis phenotypes affect organ dysfunction, inflammation, and immune response
📊 How sepsis phenotyping can improve outcomes: Tailoring treatment based on phenotype
🩺 Sepsis management: Strategies for personalized care in different sepsis phenotypes
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=KOBfVXHNDLw 
 

#86 Sepsis Advanced - Sepsis Induced Cardiomyopathy SIC or SICM Overview | Clinical Medicine

In this advanced clinical medicine podcast, we provide a comprehensive overview of Sepsis-Induced Cardiomyopathy (SIC or SICM) – a critical and often under-recognized complication of sepsis.
Covered in this podcast:
🫀 Epidemiology of sepsis-induced cardiomyopathy and incidence in ICU patients
🧬 Pathophysiology: Mechanisms behind myocardial dysfunction in sepsis
🩺 Diagnosis: Echocardiographic findings, biomarkers, and clinical challenges
💊 Treatment strategies: Hemodynamic support, inotropes, and sepsis protocols
📉 Prognosis and outcomes in patients with SICM
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=sr7W6HmVVvw 
 

#85 Sepsis Basics - Septic Shock Pathophysiology | Clinical Medicine

In this foundational clinical medicine video, we break down the basics of sepsis and septic shock, focusing on the underlying pathophysiology that drives this life-threatening condition.
✅ What is sepsis? Definitions and criteria.
🧬 Pathophysiology of septic shock: Inflammatory response, cytokine storm, vasodilation, organ dysfunction, micro thrombi, adrenal suppression, capillary permeability, mitochondrial dysfunction, multi organ failure
💉 Progression to shock: How sepsis leads to hypotension and multi-organ failure
🧪 Key clinical features and diagnostic markers
📈 Overview of current clinical understanding and relevance in critical care
🦠🦠Sepsis Playlist:
https://youtube.com/playlist?list=PLf5bMa9_tvRhC6NDyogE1sw2cdBkAOBPM&si=jE1Ioh4viA1iIJDu
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=JMjS0TOtzoI 
 

#84 Extracorporeal Membrane Oxygenation (ECMO) Basics - Comprehensive Overview | Clinical Medicine

Extracorporeal Membrane Oxygenation, more commonly referred to as ECMO, first started in the pediatric world before becoming more and more prominent in adults. It is used for patients with severe respiratory or hemodynamic failure as a means to try and support these patients long enough for their heart or lungs to recover. This video is an introduction to understanding ECMO. We discuss the general principles of what ECMO is and how it works. We then dive into the different types of ECMO, such as VV-ECMO (venovenous) and VA-ECMO (venoarterial). We illustrate the differences between these two types of ECMO, their indications, and the anatomy related to how they work. We then discuss the indications and contraindications for cannulating a patient for ECMO. We go into what needs to be done by the care team daily to maintain the ECMO circuit and optimize the patient. Lastly, we dive into the many potential complications that can result when a patient is on ECMO. 
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=WPf5I0CP_yE 
 

#83 Acute Respiratory Distress Syndrome (ARDS) Basics - Diagnose, Manage, Trials | Clinical Medicine

Acute Respiratory Distress Syndrome (ARDS) affects critically ill patients and has a very high mortality rate. The management of ARDS is critical with a number of landmark trials to help guide that management.
We talk about the Berlin Criteria used to diagnose ARDS including how to gauge ARDS severity. We then dive into the general management approach including tidal volume, plateau pressures, respiratory rate, oxygen saturation goals, pH goals, and more.
Finally, we dive into the different landmark trials as a way to understand the management of ARDS. This includes the ALVEOLI Trial on low versus high PEEP, PROSEVA Trial on proning, ACURASYS and ROSE Trials on neuromuscular blockage (paralysis), ARDS Network Trials on tidal volumes and plateau pressures, as well as fluid strategies, and the more recent DEXA-ARDS Trial on steroids for ARDS. All studies linked at the bottom.
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=tj699KeEY14 
 

#82 Cardiac Physiology Basics - Output, Index, Preload, Afterload, Contractility | Clinical Medicine

Cardiac output and cardiac index are two critical concepts to understand. We tie together preload, afterload, contractility, heart right, end diastolic volumes, the cardiac cycle, Frank Starling curves, Anrep Affect, and more in a clear and concise manner! We also talk about the physiologic things that contribute to these different variables.
Cardiac output is the amount of blood the heart squeezes out every minute. It is equal to the stroke volume times the heart rate. What contributes to these two variables though? The stroke volume is the end diastolic volume minus the end systolic volume and is affected by three things: preload, afterload, and contractility. The preload is the end diastolic volume, which is essentially the amount of blood in the ventricle right before is starts to contract in systole. As it increases, stroke volume tends to increase up until the ventricle becomes overstretched as demonstrated by the Frank Starling curve. The after load is the pressure that the ventricle has to contract against. Typically, as the after load increases the stroke volume decreases. The exception to this is the Anrep Affect, which we explain. Contractility is how powerful of a contraction the heart muscles make. As it increases, the strove volume increases. It is intimately connected to and affected by preload and afterload. Heart rate is more straightforward, but remember that there is a point where continued increases in heart rate actually decrease cardiac output given too short of time for diastolic filling. Cardiac index then is the cardiac output divided by the body surface area, which provides a more informative look at how well the body is being supplied with blood.
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=NEDln5Gc6SU 
 

#81 Mechanical Ventilation Advanced - Hemodynamics And Cardiovascular Effects | Clinical Medicine

Intubating a patient and placing them on mechanical ventilation is often used as a lifesaving technique to support a patient while giving them time to heal. Mechanical ventilation though is not a "natural" process and has a number of significant effects on the hemodynamics/cardiovascular system of the patient. We discuss the most common hemodynamic changes that are critical to know when caring for these patients. Specifically, we will illustrate mechanical ventilation's effects on the right side of the heart (venous return/preload/afterload), pulmonary vasculature (alveolar and extra-alveolar pulmonary vascular resistance), and left side of the heart (preload/afterload). 
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=GJ7ORabbVc0 
 

#80 Arterial Blood Gas Basics - Sampling, Interpreting, Clinical use, Acid-Base | Clinical Medicine

In this podcast we discuss the basics of the arterial blood gas or ABG. This is a blood draw that some may consider a small procedure. It is important for all of those in the healthcare field to understand what this is, how to perform the procedure, the various components, and how to interpret the results. Here, we go over these things and more! We talk about blood gases in general, including the arterial blood gas, capillary blood gas, and venous blood gas. 
You can sample any arterial site, but most often the radial or femoral artery. Textbooks would suggest performing the Allen's Test first, which we will review. We then go over the procedure itself.
Interpreting the ABG involves understanding the various results. This includes the measured results, being the pH, PaO2, and PaCO2. The calculated components are the base excess, HCO3, and SaO2. ABGs are great for looking at oxygenation, ventilation, and acid-base status.
We will finish with a very basic introduction to the acid-base assessments including how to identify whether it's acidotic or alkalotic and then whether it is primary respiratory or metabolic.
👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
📰👇SIGN UP FOR OUR FREE BIMONTHLY NEWSLETTER👍👍 https://whiteboarddoctor.m-pages.com/IAdAdI/wbdr-sign-up
Stay up-to-date on the most important medical, science, and healthcare news!
YouTube Video:
https://www.youtube.com/watch?v=cFkgWDbD_OQ